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As shown in Figure 4A, the hyperparameter tuning was conducted using a Latin hypercube sampling strategy, which generated 30 combinations of hyperparameters within predefined ranges (number of trees: 501500

Several studies have systematically demonstrated that CD4 + T cell subsets, such as Th1, Th17, and T follicular helper (Tfh), are involved in the development of pSS (4, 5)